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Vitamin D3 Shots
Packing:- (4x5 ML) Indications:- Osteomalacia

  • Each nano shots contains:
    Cholecalciferol IP 60000 IU (Vitamin D3 Oral Solution)

    Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight. Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are considered the main forms of vitamin d and are found in various types of food for daily intake. Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation, and bone metabolism.


    ⇛ Hypophosphatemia, Familial
    ⇛ Vitamin D Resistant Rickets
    ⇛ Parathyroid deficiency
    ⇛ Osteomalacia

    Mechanism of action

    Biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of vitamin D3 cholecalciferol (or D2) occurs in the liver to yield 25-hydroxyvitamin D while the second hydroxylation happens in the kidneys to give 1, 25-dihydroxyvitamin D. These vitamin D metabolites subsequently facilitate the active absorption of calcium and phosphorus in the small intestine, serving to increase serum calcium and phosphate levels sufficiently to allow bone mineralization. Conversely, these vitamin D metabolites also assist in mobilizing calcium and phosphate from bone and likely increase the reabsorption of calcium and perhaps also of phosphate via the renal tubules. There exists a period of 10 to 24 hours between the administration of cholecalciferol and the initiation of its action in the body due to the necessity of synthesis of the active vitamin D metabolites in the liver and kidneys. It is parathyroid hormone that is responsible for the regulation of such metabolism at the level of the kidneys.


    Cholecalciferol is readily absorbed from the small intestine moreover, bile is necessary for absorption as well. The mean central volume of distribution of cholecalciferol supplementation was approximately 237 L. The protein binding documented for cholecalciferol is 50 to 80%. Specifically, in the plasma, vitamin D3 (from either diet or the skin) is bound to vitamin D-binding protein (DBP) produced in the liver, for transport to the liver. Within the liver, cholecalciferol is hydroxylated to calcifediol (25-hydroxycholecalciferol) by the enzyme vitamin D-25-hydroxylase. At the kidney, calcifediol subsequently serves as a substrate for 1-alpha-hydroxylase, yielding calcitriol (1,25-dihydroxycholecalciferol), the biologically active form of vitamin D3. It has been observed that administered cholecalciferol and its metabolites are excreted primarily in the bile and feces. The half-life of cholecalciferol as being about 50 days.

    Side Effects

    The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however chest pain, feeling short of breath, muscle or bone pain,constipation, nausea, and vomiting may occur in some patients.


    ⇛ High levels of vitamin D in your body
    ⇛ High levels of calcium in your blood
    ⇛ Malabsorption
    ⇛ Heart disease
    ⇛ Kidney disease
    ⇛ Electrolyte imbalance


    Carefully use this product in the following conditions: ⇛ Arrhythmia
    ⇛ Electrolyte imbalance
    ⇛ Hypercalcemia
    ⇛ Renal dysfunction
    ⇛ Hepatobiliary dysfunction

    Disclaimer:The data uploaded is made from content already available on internet.The company holds no right of it and is not responsible for any wrong information.

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